Delayed Embryonic Development and Implantation in Senescent Golden Hamsters1

Early human embryonic development: individuation before implantation.

Tumor ¡genesisStudies with 1,2-Dimethylhydrazine Dihydrochloride, Hydrazine Sulfate, and Isonicotinic Acid in Golden Hamsters1

Solutions of 0.012% hydrazine sulfate, 0.001% 1,2-dirnethylhydrazine dihydrochloride, and 0.5% isonicotinic acid were given continuously in the drinking water of 9-, 7-, and 5-week-old randomly bred Syrian golden hamsters for the remainder of their lifetime. The consumption of hydrazine sulfate and isonicotinic acid was without any significant carcinogenic action, while 1,2-dimethylhydrazine di...

Speech development and auditory performance in children after cochlear implantation

 Abstract Background: The aim of this study was to determine the auditory performance of congenitally deaf children and the effect of cochlear implantation (CI) on speech intelligibility. Methods: Aprospective study was undertaken on 47 children in a pediatric tertiary referral center for CI. All children were deaf prelingually and were younger than 8 years of age. They were followed up until 5...

Regulation of embryonic implantation.

The preimplantation embryo produces several factors during its development to signal its presence to the maternal organism. This paper will focus on the role of two distinctive cytokine and growth factor systems (interleukin-1 (IL-1) system and the vascular endothelial growth factor (VEGF) system) during early embryonic development and implantation. IL-1 receptor is expressed in the endometrium...

Identification of differentially expressed proteins in senescent human embryonic fibroblasts.

Normal human fibroblasts undergo a limited number of divisions in culture, a process known as replicative senescence (RS). Although several senescence-specific genes have been identified, analysis at the level of protein expression can provide additional insights into the mechanisms that regulate RS. We have performed a proteomic comparison between young and replicative senescent human embryoni...